Panama Canal Cruises

Featured Sailings

Featured the Panama Canal Cruise Deals

Sailings on some of the newest ships cruising the Panama Canal, picked from our booking engine and refreshed daily. Open any sailing for current availability, or ask an advisor to price it for your dates.

16 Days

Panama Canal

16 Days Panama Canal

Princess Cruises · Star Princess

Departs: Apr 3, 2027
Itinerary: Fort Lauderdale, Aruba, Panama Canal, Fuerte Amador, Mazatlan, Cabo San Lucas, Los Angeles

Published prices from

$104per day* (from $1,659 per person) taxes, fees & port charges incl.

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19 Days

Panama Canal

19 Days Panama Canal

Holland America Line · Nieuw Amsterdam

Departs: Dec 20, 2026
Itinerary: Fort Lauderdale, Half Moon Cay, Grand Turk, Amber Cove, Key West, Fort Lauderdale, Half Moon Cay, Oranjestad, Cartagena/Colombia, Panama Canal, Gatun Lake/Panama, Panama Canal, Colon, Puerto Limon, George Town, Fort Lauderdale

Published prices from

$136per day* (from $2,579 per person) taxes, fees & port charges incl.

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6 Days

Central America

6 Days Central America

Carnival Cruise Line · Carnival Liberty

Departs: Nov 2026 – Nov 2027
Itinerary: New Orleans, Belize City, Cozumel, New Orleans

Published prices from

$56per day* (from $335 per person) taxes, fees & port charges incl.

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*Per day price is the lowest published per-person fare divided by the number of cruise days. Fares change often and are confirmed at booking. See all the Panama Canal cruises →

Cruise Lines

Cruise Lines That Sail to the Panama Canal

The lines with the Panama Canal sailings in our booking engine right now, most sailings first.

Carnival Cruise Line164 sailingsView cruises
Princess Cruises131 sailingsView cruises
Royal Caribbean101 sailingsView cruises
Holland America Line71 sailingsView cruises
Cunard46 sailingsView cruises
MSC Cruises45 sailingsView cruises
Windstar Cruises45 sailingsView cruises
Norwegian Cruise Line37 sailingsView cruises
Viking Ocean Cruises34 sailingsView cruises
Crystal Cruises31 sailingsView cruises
Oceania Cruises25 sailingsView cruises
Seabourn22 sailingsView cruises

Departure Ports

Popular Ports for the Panama Canal Cruises

Where the Panama Canal cruises leave from, ranked by the number of sailings in our booking engine. Pick a port to see its the Panama Canal cruises.

Numbers show sailings currently listed from each port. Port guides: Fort Lauderdale, Miami, Tampa, Galveston, New Orleans, Los Angeles, Southampton, San Diego. See all departure ports →

Destination Advice

the Panama Canal Cruise Advice

Planning guides from our advisors and the latest news for the Panama Canal cruisers.

Cruise GuidePanama Canal Cruises: Full Transit or Partial Transit?How full and partial Panama Canal transits differ, the best months to sail, where cruises leave from, and which lines to consider.Read more

More cruise advice →

Google Reviews

What Our Clients Say

Real reviews from travelers our advisors have helped, straight from Google.

    
 
 
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   Marty Wagner 
 
 
 
 Trustindex verifies that the original source of the review is Google. I (we) have been booking cruises with The Cruise Company since the early 90s. Angelina is quite simply our go-to for cruise bookings...now after some 40 cruises taken! Thank you Angelina, as always, for your great personalized service!
  
 
      Posted on Google  
   
   Haik Yapoudjian 
 
 
 
 Trustindex verifies that the original source of the review is Google. I have booked cruises with your company for 20+ years.  Most professional, VIP and Five Star Service each and every time!  Thank you for helping me book 27 cruises including friend and family.
  
 
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   Chrissie F 
 
 
 
 Trustindex verifies that the original source of the review is Google. Great communication and awesome job with providing thorough information on cruise options. Quick response time! Still fighting with spouse on which cruise choice to go with and appreciate their patience with answering our on demand questions.
  
 
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   Cari Brandt 
 
 
 
 Trustindex verifies that the original source of the review is Google. Literally the best agency I’ve worked with. Been through quite a few and none of them have compared! Thank you guys for the best vacation and making it so stress free.
  
 
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   Taye Luke 
 
 
 
 Trustindex verifies that the original source of the review is Google. What wonderful service! I had such a fantastic trip with my family. Very easy to work with and very low stress for me. Would totally book again through this company!
  
 
      Posted on Google  
   
   Alyssa Marques 
 
 
 
 Trustindex verifies that the original source of the review is Google. Wow! I have never had such a great experience with any other travel agency! Super professional and personable, would definitely recommend!